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Chemotherapy

What Is Chemotherapy?

Chemotherapy is a medications that damage the cells divide into the body.

Unlike surgery or radiation, chemotherapy works all over the body and is not focused. This means that it can eliminate cancerous lesions, such as metastasis, that have developed in various organs of the body.

Chemotherapy’s impact has a range of side effects such as hair loss, loss of appetite, changes to bowel movements, fatigue, infection, hemorrhaging, incontinence, pain, and more.

Chemotherapy will be given with or without radiation

Examples of standard chemotherapy protocols for treating pancreatic cancer:

Folfirinox is a combination of 4 anti cancer drugs:

  1. Leucovorin
  2. Adrucil®, (Fluorouracil, 5-FU)
  3. Camptosar®, Campto®, (Irinotecan)
  4. Eloxatin®, (Oxaliplatin)

Gemzar®, gemcitabine and one or two of this drugs:

Examples of standard chemotherapy protocols for treating breast cancer:

Examples of standard chemotherapy protocols for treating skin cancer or Melanoma:

Chemotherapy innovation

Facts

  1. The existing therapies used on stage 4 metastatic cancer are not curative, and this is a source to the need for innovative and effective treatment strategies in order to fight the disease.
  2. The National Cancer Institute, NCI, highlights the fact that for a certain group of cancer patients, the best treatment option is to join one of the many clinical trials existing worldwide aiming to increase their chances of therapeutic success.
  3. Currently, every patient will be offered the standard protocols described above. Sometimes the oncologist may suggest integrating these therapies with trials carried out in the institute.

The opportunity

  1. Advances in cancer therapies may be found in clinical trials prescribing cutting edge, innovative drugs, some of which have already been recognized by the US Food & Drug Administration, the FDA, as “breakthrough drugs” and require further information to be approved.
  2. An entire world of clinical trials, Compassionate drugs and advanced new cancer treatments are available worldwide.
  3. It is important to know and have access to cutting edge cancer treatments that best match the unique medical condition of the patient and increase chances in winning the fight against compared to the standard care offered.

Read our publications on innovative treatments and chemotherapies:

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We support access to and expand cancer treatments beyond the standard of care, with the most advanced and innovative treatment options in the world, personally matching the individual cancer patient’s medical condition and with the support of top tier oncologists.

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Pancreatic cancer – Keep reading Earl Groce’s success with CPI-613

No sign of cancer!

Groce has been a part of a clinical trial since his diagnosis four-plus years ago and the results have been tremendous –just recently, his MRI and CT scan revealed continued good results – no sign of cancer. His CA 19-9 levels remain in a normal range – also a good sign.

At 72, Groce has had 98 rounds of chemotherapy through a clinical trial for CPI-613, a targeted therapy aimed at cancer cell metabolism. He receives the test drug in addition to the Standard of Care protocol which is FOLFIRINOX, a combination of three chemotherapeutic agents. He joined the clinical trial as a phase I study participant. The study is currently in an advanced phase, phase III.

Gross is undoubtedly free of a disease that is known to be extremely aggressive due to the fact that he participated in the study. Because of this, he received an innovative drug that was not available to other patients not participating in the study and would go on for several years until the final approval of CPI-613, which would then be available to all patients.

Pancreatic cancer patients who participate in clinical research have better outcomes. Every treatment available today was approved through a clinical trial. The Pancreatic Cancer Action Network (PanCAN) strongly recommends clinical trials at diagnosis and during every treatment decision.

“If you get a chance to enroll in a clinical trial, please consider it. Do it for your sake and the sake of future patients”, says Groce.

About Pancreatic Cancer

Pancreatic cancer occurs when cancer cells develop in the tissues from which the pancreas is made.

This type of cancer is aggressive, since most of the patients are diagnosed in an advanced stage, where the disease is considered incurable, for the most part.

Pancreas cancer is hard to diagnose early since its symptoms do not usually appear in early stages.

In many cases until the patient is diagnosed with a pancreatic cancer there are already metastases elsewhere in the body (stage 4 metastatic pancreatic cancer).

The patient’s life expectancy is poor and currently stands on less than one year; this is with the support of the standard treatments.

To improve patients’ chances, the American Society for Clinical Oncology, ASCO, that includes various specialists in its panel, such as oncologists, radiologists, gastrologists among others, guides oncologists to inform pancreatic cancer patients in all topics related to clinical trials in every stage of their disease.

The National Cancer Institute, NCI, of the United States, stresses that for pancreatic cancer patients, the preferred treatment option is to join one of the many clinical trials around the world and thus increase the chances of success over the standard protocols.

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