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Keytruda

What is Keytruda® is and what it is used for?

Keytruda® is a prescription medicine used to treat:

  • Skin cancer called melanoma. Keytruda® may be used when your melanoma has spread or cannot be removed by surgery (advanced melanoma).
  • Lung cancer called non-small cell lung cancer (NSCLC). Keytruda®  may be used when your lung cancer:

* has spread (advanced NSCLC) and,

* tests positive for “PD-L1” and,

– you have not received chemotherapy to treat your advanced NSCLC and your tumor does not have an abnormal “EGFR” or “ALK” gene, or
– you have received chemotherapy that contains platinum to treat your advanced NSCLC, and it did not work or it is no longer working, and
–  if your tumor has an abnormal “EGFR” or “ALK” gene, you have also received an EGFR or ALK inhibitor medicine and it did not work or is no longer working.

  • Head and neck squamous cells cancer (HNSCC). Keytruda® may be used when your HNSCC:
    * has returned or spread (advanced HNSCC) and
    * you have received chemotherapy that contains platinum to treat your advanced HNSCC, and it did not work or is no longer working.
    cancer called classical Hodgkin lymphoma (cHL) in adults and children when:
    * you have tried a treatment and it did not work or
    * your cHL has returned after you received 3 or more types of treatment.
  • Bladder and urinary tract cancer called urothelial carcinoma. Keytruda® may be used when your bladder or urinary tract cancer:
    * has spread or cannot be removed by surgery (advanced urothelial cancer) and
    * you are not able to receive chemotherapy that contains a medicine called cisplatin, or
    * the disease has progressed during or after you have received chemotherapy that contains platinum.
  • Cancer that is shown by a laboratory test to be a microsatellite instability-high (MSI-H) or a mismatch repair deficient (dMMR) solid tumor. Keytruda® may be used in adults and children to treat:
    * cancer that has spread or cannot be removed by surgery (advanced cancer), and
    * has progressed following systemic treatment, and you have no satisfactory treatment options, or
    * you have colon or rectal cancer, that has progressed although you have received chemotherapy treatment with fluoropyrimidine, oxaliplatin, and irinotecan.
    It is not known if Keytruda® is safe and effective in children with MSI-H cancers of the brain or spinal cord (central nervous system cancers).
  • Stomach cancer called gastric or gastroesophageal junction (GEJ) adenocarcinoma that tests positive for “PD-L1”, when:
    * the cancer has returned or spread (advanced gastric cancer), and
    * you have received 2 or more types of chemotherapy including fluoropyrimidine and chemotherapy that contains platinum, and
    * if your tumor has an abnormal “HER2/neu” gene, and you also received a HER2/neu-targeted medicine.

How will you receive Keytruda®?

Always use Keytruda® as instructed by the doctor. You should check with your doctor or pharmacist if you are not sure. The dosage and duration of treatment will be determined by the doctor only.

  • Your doctor will give you Keytruda® into your vein through an intravenous (IV) line over 30 minutes.
  • Keytruda® is usually given every 3 weeks.
  • Your doctor will decide how many treatments you need.
  • Do not exceed the recommended dose

Therapeutic group: Antineoplastic agents, humanized monoclonal antibody.
All rights reserved to Merck Sharp & Dohme Corp., New-Jersey, USA.

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The amazing story of Stephen, a metastatic colorectal cancer patient who saved himself

1 out of 25 metastatic colorectal cancer patients is MSI-H, let’s not miss any of them…

Stephen was diagnosed at the age of 28 with metastatic colorectal cancer. About 20% of newly diagnosed colorectal cancer patients are diagnosed at an advanced stage, stage 4, of which the cancer has spread (metastasized) to other organs in the body besides the colon.

Stephen wanted and wants to live. He started learning by himself the disease and the different treatments for it. He found out about MSI, got tested to find out whether his tumor harbor MSI-H and indeed, it did. In the next step, he brought up to his treating oncologist the possibility of participating in an appropriate clinical trial.

He was enrolled to the study … and was saved!

Amazing! The power lies in your hands! Be active – don’t give up!

We are here to help you!

To watch the inspiring story of Stephen:

1 out of 25 metastatic colorectal cancer patients is MSI-H, let’s not miss any of them… Stephen was diagnosed at the age of 28 with metastatic colorectal cancer. About 20% of newly diagnosed colorectal cancer patients are diagnosed at an advanced stage, stage 4, of which the cancer has spread (metastasized) to other organs in the body besides the colon. Stephen wanted and wants to live. He started learning by himself the disease and the different treatments for it. He found out about MSI, got tested to find out whether his tumor harbor MSI-H and indeed, it did. In the next step, he brought up to his treating oncologist the possibility of participating in an appropriate clinical trial. He was enrolled to the study … and was saved! Amazing! The power lies in your hands! Be active – don’t give up! We are here to help you! To watch the inspiring story of Stephen

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