Is an immunotherapy approved drug on its way to treat Small Cell Lung Cancer, SCLC?

About Orphan Drug and the “CASPIAN” –

The FDA has granted an orphan drug designation to “Durvalumab” (“Imfinzi”) for the treatment of patients with small cell lung cancer, SCLC.

Data supporting the orphan drug designation come from the phase III “CASPIAN” trial, which met its primary endpoint and announced in end of June 2019. In patients with extensive-stage SCLC, the addition of Durvalumab to standard chemotherapy demonstrated a statistically and clinically meaningful improvement in overall survival.

An orphan drug designation is granted to new therapies intended to treat rare diseases that affect less than 200,000 in the United States and allows for increased assistance from the FDA from the drug company for the final approval. SCLC accounts for about 15% of all lung cancer diagnoses and has a 5-year survival rate of approximately 6%.

About Imfinzi –

Durvalumab has received FDA approval for the treatment of patients with unresectable, stage III non–small cell lung cancer after chemoradiotherapy and for the treatment of previously treated patients with advanced bladder cancer.

The PD-L1 inhibitor is currently being investigated worldwide in patients with limited-stage SCLC in the phase III “ADRIATIC” trial.

The best treatment for a cancer patient is to get the most advanced cancer drugs in advanced stages of development. There, the hope and the chance to extend life go far beyond the standard protocols.



Do not give up on life!

Contact us 24/7 for free service matching:

Call center +44.2082.426.039


For further reading

To check if our service suits your case
We need to talk

Improve therapeutic outcomes, prolong life and quality of life, is our main business.
We support access to and expand cancer treatments beyond the standard of care, with the most advanced and innovative treatment options in the world, personally matching the individual cancer patient’s medical condition and with the support of top tier oncologists.

Article categories

קטגוריות המאמרים

Popular topics