Letrozole – A Traditional Therapy, but Not the Only One
Letrozole is a long-standing hormonal therapy used to treat estrogen receptor-positive (ER+) breast cancer, especially in postmenopausal women.
It belongs to a class of drugs called aromatase inhibitors and works by lowering estrogen levels to slow cancer growth.
How Does Letrozole Work?
- Letrozole prevents the body from producing estrogen, which fuels the growth of ER+ cancer cells.
- It is typically prescribed as a long-term treatment, sometimes after surgery or chemotherapy.
- Common side effects include fatigue, joint pain, and bone density loss.
Is Letrozole Still the Best Option Today?
Letrozole was considered a breakthrough 20 years ago, but today, more advanced and effective treatment options exist – often with fewer side effects and better outcomes for patients.
❗ Relying only on Letrozole is like driving a car from 2003 while others are already in electric vehicles.
What Are the Modern Alternatives?
In cases of metastatic or Letrozole-resistant breast cancer, physicians may consider:
- Modern biological treatments (such as CDK4/6 inhibitors – Palbociclib, Abemaciclib, Ribociclib)
- Targeted therapies based on genetic profiling (ESR1, PIK3CA, BRCA, and more)
- Advanced combinations with hormonal therapy
- Participation in cutting-edge clinical trials
How Can Trial-In Pharma Help?
At Trial-In Pharma, we specialize in guiding patients beyond Letrozole – toward the most advanced treatment solutions available worldwide.
- Scanning for targeted therapies based on biopsy and genetic test results
- Locating clinical trials in Israel and abroad
- Helping patients access medications not available through standard healthcare
- Providing ongoing professional support throughout the treatment journey
When Should You Reach Out?
If you’re still being treated with Letrozole alone – it may be time to explore better options. Contact us and together we’ll evaluate advanced therapies tailored to your specific condition.
