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Ibrance®, palbociclib, is a kinase inhibitor indicated for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer in combination with
• an aromatase inhibitor as initial endocrine based therapy in postmenopausal women e.g. Letrozole


• fulvestrant in women with disease progression following endocrine therapy

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