CTLA-4, Cytotoxic T lymphocyte antigen 4, is a protein found on cytotoxic T cells of the immune system, designed to control cells and prevent them from harming normal cells, thus preventing autoimmune and allergic diseases. In cancer patients, CTLA-4 expression causes cytotoxic T cells not to act against cancer cells. For further reading see the entry of “Immunosuppressive barrier”.
Alternative Meanings:
- CTLA-4CTLA-4 is a protein found on cytotoxic T cells of the immune system, designed to control cells and prevent them from harming normal cells, thus preventing autoimmune and allergic diseases. In cancer patients, CTLA-4 expression causes cytotoxic T cells not to act against cancer cells. For further reading, see the entry of “Immunosuppressive barrier”.