Immune barriers are the regulators of the immune system. These pathways are essential for tolerance processes and prevent autoimmune diseases, ie, those pathways that prevent the immune system from acting against the body itself. In cancer, these pathways are activated and as a result, the immune system does not attack the cancer. This way of cancer thrive in the body PD-L1 and CTLA-4 are types of training barriers. This therapeutic strategy has revolutionized the treatment of cancer in recent years and is one of the most studied strategies in the world for many types of cancer and different stages of treatment.
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