According to a new study cancer patients with cholangiocarcinoma
(bile duct cancer) with a BRAF V600E mutation can benefit from treatment with two biological drugs included in the melanoma health basket. This is only 5% of all cholangiocarcinoma patients.
These advanced and innovative drugs are Tafinlar® (Dabrafenib) and Mekinist® (Trametinib) of Novartis®
The intermediate results observed in the study were similar to the standard treatment, which is a combination of two chemotherapies, a Gamzer and Cisplatin given as first line treatment for advanced disease. Therefore, this combination is more successful because the patient will not tolerate the severe side effects of chemotherapy and will benefit from biological therapy with far fewer side effects.
The combination of Tafinlar® and Mekinist® is effective not only in cholangiocarcinoma but also in melanoma, lung cancer and anaplastic thyroid cancer.
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