Epidermal Growth Factor Receptor, EGFR, is a receptor found on many cells that is the receptor of the EGF growth hormone. When EGFR binds to the EGFR receptor, there will be an increase in the EGFR level on the cancerous cell. to be involved in the growth and spread of cancerous cells.
Tarceva®, erlotinib, is a drug potently inhibits the intracellular phosphorylation of EGFR.