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Promising efficacy with a new combination of 2 approved drugs – Lenvima plus Keytruda

Published on January 21, 2020

Background

In this trial, 137 cancer patients with NO AVAILABLE STANDARD THERAPEUTIC OPTIONS were treated with the combination of Lenvima plus Keytruda.

Eligible patients had metastatic Renal Cell Carcinoma (RCC), Endometrial Cancer, Squamous Cell Carcinoma of the Head and Neck (SCCHN), Melanoma, Non-Small-Cell Lung Cancer (NSCLC) and Urothelial Cancer.

Results

At 24 weeks, this is the percentage of patients that were still responding to the combination and their cancer has stopped from continuous growing and/or has shrunk:

Adverse Events

The most common treatment-related adverse events were fatigue (58%), diarrhea (52%), hypertension (47%), and hypothyroidism (42%).

Conclusion

The combination of Lenvima plus Keytruda had promising efficacy among patients with selected solid tumors, with a manageable safety profile.

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