Background Epidermal Growth Factor Receptor, EGFR, mutations are one of the most common driver mutations in Non–Small-Cell Lung Cancer, NSCLC. Tagrisso, a third-generation EGFR tyrosine kinase inhibitor, TKI, is approved…
Purpose This Phase 1/2 study evaluated safety and efficacy of a topical anhydrous ointment, SOR007, which contains submicron particles of the chemotherapy Taxol primarily in breast cancer patients with cutaneous…
Overview Cervical cancer is a malignant tumor that grows in different parts of the cervix. The vast majority of cervical cancers are linked to an infection by the human papillomavirus…
Background Patients with advanced or metastatic esophageal cancer of squamous cell type have poor prognosis. For these patients, treatment options are limited after first therapy. Tislelizumab is a humanized monoclonal…
Background Castration-sensitive prostate cancer, CSPC, is cancer that is controlled by keeping the testosterone level as low as would be expected if the testicles were removed. Metastatic prostate cancer is…
Background Metastatic Triple Negative Breast Cancer, mTNBC, has limited treatment options for patients and thus represents a highly unmet need. In this phase Ⅱ trial, the investigators evaluated the combination…
Background Patients with platinum-resistant ovarian cancer have limited therapeutic options available to them. Treatment is largely comprised of chemotherapy, which is known to have limited efficacy where just 4% and…
Background According to data from the CHOICE-1 trial, Toripalimab (anti–PD-1) in combination with chemotherapy showed significant improvement in the length of time until progression of the disease (Also called, Progression-Free…
Overview Glioblastoma, GBM, is a type of cancer that affects the central nervous system. It stems from astrocytes, which are special cells that support the neurons. This cancer can arise…
Overview Serous ovarian cancer is a relatively uncommon tumor that could be quite challenging to manage, especially when it’s recurrent. Among women, ovarian cancer is the 5th most common type…