Overview Colorectal cancer is one of the most common types of malignant tumors in humans. According to statistics, the risk of developing this tumor in a lifetime is: Around 1…
Background Biliary tract cancer is a group of malignancies that includes intrahepatic and extrahepatic cholangiocarcinoma, gallbladder cancer, and ampulla of Vater cancer. It is typically diagnosed at advanced stages for…
Importance Endometrial cancer is often hormone-dependent and treated with aromatase inhibitors, (AIs). The uncontrolled PI3K-AKT-mTOR pathway observed in this type of cancer drives hormonal resistance. Therefore, there is rationale of…
Background Epidermal Growth Factor Receptor, EGFR, mutations are one of the most common driver mutations in Non–Small-Cell Lung Cancer, NSCLC. Tagrisso, a third-generation EGFR tyrosine kinase inhibitor, TKI, is approved…
Purpose This Phase 1/2 study evaluated safety and efficacy of a topical anhydrous ointment, SOR007, which contains submicron particles of the chemotherapy Taxol primarily in breast cancer patients with cutaneous…
Overview Cervical cancer is a malignant tumor that grows in different parts of the cervix. The vast majority of cervical cancers are linked to an infection by the human papillomavirus…
Background Patients with advanced or metastatic esophageal cancer of squamous cell type have poor prognosis. For these patients, treatment options are limited after first therapy. Tislelizumab is a humanized monoclonal…
Background Castration-sensitive prostate cancer, CSPC, is cancer that is controlled by keeping the testosterone level as low as would be expected if the testicles were removed. Metastatic prostate cancer is…
Background Metastatic Triple Negative Breast Cancer, mTNBC, has limited treatment options for patients and thus represents a highly unmet need. In this phase Ⅱ trial, the investigators evaluated the combination…
Background Patients with platinum-resistant ovarian cancer have limited therapeutic options available to them. Treatment is largely comprised of chemotherapy, which is known to have limited efficacy where just 4% and…