Background On average, KRAS is mutated in approximately 50% of patients with colorectal cancer. Chemotherapy in combination with targeted drugs is standard of care option for patients with metastatic colorectal…
Background Treatment options for recurrent ovarian cancer are of limited clinical benefit and adversely affect patient quality of life, representing an unmet need for tolerable and effective therapies. About the…
Background Melanoma is a serious form of skin cancer that begins in cells known as melanocytes. Melanoma is dangerous because it can rapidly spread to other organs in the body…
Background Patients with advanced or metastatic breast cancer have very few effective treatment options. The lack of successful therapeutic strategies is reflected by a low 5-year survival. There continues to…
Background - Glioblastoma and MDNA55 The interleukin-4 receptor–targeted immunotherapeutic MDNA55 has demonstrated improved survival and disease control in patients with recurrent Glioblastoma who are treated at high dose, irrespective of…
Background A Phase 2 multi-center study was conducted to evaluate the virus, DNX-240, also called Tasadenoturev, in combination with the immunotherapy, Keytruda, in pateints with recurrent glioblastoma. Methods Patients with…
Background Anthracyclines is a class of drugs used in cancer chemotherapy. A wildly used Anthracycline drug is Doxorubicin also known as Adriamycin. These drugs are used to treat many cancers,…
Background This clinical trial assessed the efficacy and safety of Camrelizumab plus Rivoceranib in patients with advanced liver cancer. Camrelizumab is anti-PD-1 immunotherapy drug given intravenous. Rivoceranib, also known as…
Background - Colorectal cancer and coffee Several compounds found in coffee possess antioxidant, anti-inflammatory and insulin-sensitizing effects, which may contribute to anticancer activity, including colorectal cancer. Epidemiological studies have identified…
Background Concurrent chemoradiation therapy remains the standard therapy for unresectable Esophageal Squamous Cell Carcinoma patients. However, its feasibility and efficiency for older patients are being challenged. Serious acute toxic effects,…