Combination of Two FDA Approved Drugs Shows Promise in BRAF V600E‒Mutated Glioma
In short The results of a phase II trial in patients with BRAF V600E mutations in high- and low-grade glioma, were reported at the 24th meeting of the Society for…
Potential Cure of recurrent GBM with the Oncolytic Herpes Virus G47∆
Interim results The virus has been designated a breakthrough therapy in Japan. An interim analysis of a trial of the oncolytic herpes virus G47∆ has shown a 1-year survival rate…
Glioblastoma Moltiforme, GBM – NEW immunotherapies stop from growing in newly diagnosed patients
Background According to interim findings of a phase II trial, the combination of INO-5401, a T-cell–activating immunotherapy and INO-9012, an immune activator of a different kind with Libtayo (Cemiplimab, a…
New anti-cancer drug, Tucatinib, reduces risk of death in metastatic HER2+ breast cancer
Background There is significant unmet medical need following treatment with Herceptin, Perjeta and Kadcyla in patients with metastatic HER2-positive breast cancer. In the HER2CLIMB trial, the addition of tucatinib to…
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Approved immunotherapy has shown a positive survival benefit in HER2+ breast cancer
This time, we'll start from the end... Results of the study First of all, it is important to note that the research goals were not achieved in the entire study…
Small Cell Lung Cancer, SCLC – Treatment with an approved drug, Onivyde, shows efficacy
Many small cell lung cancer patients rapidly relapse due to the aggressive nature of the disease. While the current standard of care in the second-line setting can extend survival, treatment…
Lung cancer patients, heard already about Capmatinib?
The Food and Drug Administration, the FDA, has granted capmatinib a “breakthrough therapy” designation as a first-line treatment for Non-Small Cell Lung Cancer (NSCLC) patients with MET mutation, EGFR Wild-type…
This Trial Achieved Complete Disappearance of Disease in Metastatic Kidney Cancer
The main therapeutic objectives in treating metastatic disease are prolonging life (also called “Survival”) and Quality of Life (QoL), knowing the disease will stay in the body for life. ***…
Pancreatic Cancer – between 2 to 3 times survival with SM-88
Background The National Comprehensive Cancer Network, NCCN, is the health body which sets the world guidelines in treating cancer. The NCCN recommends clinical trials as the preferred option over current…
New drug may become the new standard of care for patients with small cell lung cancer, SCLC
Don't miss opportunities to get drugs like this in a clinical trial setting! Why? Lurbinectedin monotherapy as a second-line therapy in patients with small cell lung cancer, SCLC, elicited a…