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Personalized Cancer Vaccines: The Neoantigen Revolution

Personalized Cancer Vaccines: The Complete Guide

A comprehensive review of the revolution in immunotherapy: From Germany to the USA

Who are the leading companies worldwide?

There are several global biotech companies developing personalized vaccines, including Moderna (USA), BioNTech and CureVac (Germany), and PreciOnco. At Trial-In Pharma, we work with the most advanced centers and match the patient to the right destination.

Who does this page focus on?

As an example of the process, we present here the protocol of the German company PreciOnco, which offers a unique pathway for neoantigen identification. We accompany patients choosing this and other pathways worldwide.

What is the estimated cost?

Costs vary between countries and providers. In PreciOnco's case, the cost is staged: an initial payment for analysis followed by a payment for production (Full details further down the page).

What is Trial-In Pharma's role?

We are your bridge. We are not the "vaccine company" but the professional body accompanying you, making information accessible, and managing medical and logistical contact with centers abroad.

Treatment Pathway Example: PreciOnco

PreciOnco from Germany is one of the pioneers in the field of genetic diagnostics and personalized immunotherapy.

Visit PreciOnco Website >>

Important Clarification: Medical responsibility for the treatment lies solely with the provider performing it (in this case, PreciOnco). Trial-In Pharma provides accompaniment, coordination, and professional support services only, and is not the treating medical entity.

How does it work? (PreciOnco Model)

1

Analysis and Planning Phase

At this stage, the executing company analyzes the tumor:

  • 🧬
    Genetic Sequencing: Comparing tumor sample to blood sample.
  • 🔍
    Mutation Detection: Identifying the unique targets (neoantigens) of your specific cancer.
2

Production and Vaccination Phase

After analysis, the vaccine is produced:

  • ⚗️
    Peptide Production: Producing 15–20 unique peptides in the laboratory.
  • 💉
    Series of Injections: Administering the vaccine combined with immune stimulants (Adjuvants) at the medical center.

Annual Treatment Protocol

Treatment requires travel to the medical center only for injection dates.

4 Injections in the initial phase
10 Maintenance injections during the year
14 Total injections

What does the package include?

  • Full and deep genetic diagnostics
  • Personalized design and production of peptides
  • 14 injections and treatments at the medical center
  • Multidisciplinary discussion (Tumor Board)
  • Ongoing monitoring of immune response in blood

What is not included?

  • Imaging (CT / MRI) - must be brought from home
  • Flights and stay abroad (patient's responsibility)

Treatment Costs (PreciOnco Example)

Payment is staged and transferred directly to the provider according to stage progress

Stage 1: Process Initiation & Analysis
€19,450
Stage 2: Vaccine Production & Treatment
€60,000
Total estimated cost: €79,450

Why go through this process with Trial-In Pharma?

The world of cancer vaccines is developing fast, with centers in Germany, USA, and other countries. We provide you with the professional compass:

  • Global Mapping: We know the different companies (PreciOnco, Moderna, etc.) and know how to direct you to the right place for your condition.
  • Medical & Scientific Support: Our oncologists and biologists analyze the data and ensure you are in good hands.
  • Logistic Bridge: Managing bureaucracy, documents, and coordination with centers abroad, so you can focus on health.
  • Monitoring & Control: We are with you all the way, monitoring results and maintaining continuous contact with the treating center.

Want to check eligibility for a personalized vaccine?

We are here to make sense of things, explain options, and accompany you hand-in-hand to leading companies in Germany, USA, and worldwide.

Contact us for consultation and eligibility check >>

To check if our service suits your case
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Improve therapeutic outcomes, prolong life and quality of life, are our main business.
We support access to and expand cancer treatments beyond the standard of care, with the most advanced and innovative treatment options in the world, personally matching the individual cancer patient’s medical condition and with the support of top tier oncologists.

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